COST EFFECTIVENESS OF ALLOGENIC PANCREATIC ISLET TRANSPLANTATION VERSUS WHOLE PANCREAS TRANSPLANTATION IN THE UNITED KINGDOM
نویسندگان
چکیده
منابع مشابه
Islet and Pancreas Transplantation
Islet allotransplantation for patients with brittle type 1 diabetes mellitus (T1DM) is a minimally invasive and relatively safe procedure that can induce sustained, normalized glucose control and restore C-peptide secretion, with reduction of hypoglycemic episodes, stabilization or delay of chronic complications, and better quality of life. Current immunosuppressive protocols have significantly...
متن کاملPancreas and islet cell transplantation.
Currently, for the patient with type 1 diabetes, a definitive treatment without resorting to the use of exogenous insulin can be achieved only with pancreas or islet cell transplantation. These means of restoring beta-cell mass can completely maintain essentially normal long-term glucose homeostasis, although the need for powerful immunosuppressive regimens limits their application to only a su...
متن کاملPancreatic Islet Transplantation
Treatment for, and the prognosis of, type-1 diabetes mellitus (T1DM) has progressed dramatically during the last century, but the disease remains a major cause of morbidity and mortality. Although precise fi gures are not available, over 1 million United States citizens currently live with the disease, with approximately 30,000 new cases diagnosed in the US each year. The total number of people...
متن کاملPancreatic islet transplantation
BACKGROUND No formulation of exogenous insulin available to date has yet been able to mimic the physiological nictemeral rhythms of this hormone, and despite all engineering advancements, the theoretical proposal of developing a mechanical replacement for pancreatic beta cell still has not been reached. Thus, the replacement of beta cells through pancreas and pancreatic islet transplantation ar...
متن کاملALLOGENIC BONE MARROW TRANSPLANTATION IN APLASTIC ANEMIA
Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...
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ژورنال
عنوان ژورنال: Value in Health
سال: 2016
ISSN: 1098-3015
DOI: 10.1016/j.jval.2016.03.1304